Tuesday, November 23, 2021

The abstract many are talking about--because it provides new evidence of profound and long-lasting inflammation associated with damage caused by mRNA COVID vaccines

Originally publishedCirculation. 2021;144:A10712

    Our group has been using the PULS Cardiac Test (GD Biosciences, Inc, Irvine, CA) a clinically validated measurement of multiple protein biomarkers which generates a score predicting the 5 yr risk (percentage chance) of a new Acute Coronary Syndrome (ACS). The score is based on changes from the norm of multiple protein biomarkers including IL-16, a proinflammatory cytokine, soluble Fas, an inducer of apoptosis, and Hepatocyte Growth Factor (HGF)which serves as a marker for chemotaxis of T-cells into epithelium and cardiac tissue, among other markers. Elevation above the norm increases the PULS score, while decreases below the norm lowers the PULS score.The score has been measured every 3-6 months in our patient population for 8 years. Recently, with the advent of the mRNA COVID 19 vaccines (vac) by Moderna and Pfizer, dramatic changes in the PULS score became apparent in most patients.This report summarizes those results. A total of 566 pts, aged 28 to 97, M:F ratio 1:1 seen in a preventive cardiology practice had a new PULS test drawn from 2 to 10 weeks following the 2nd COVID shot and was compared to the previous PULS score drawn 3 to 5 months previously pre- shot. Baseline IL-16 increased from 35=/-20 above the norm to 82 =/- 75 above the norm post-vac; sFas increased from 22+/- 15 above the norm to 46=/-24 above the norm post-vac; HGF increased from 42+/-12 above the norm to 86+/-31 above the norm post-vac. These changes resulted in an increase of the PULS score from 11% 5 yr ACS risk to 25% 5 yr ACS risk. At the time of this report, these changes persist for at least 2.5 months post second dose of vac. We conclude that the mRNA vacs dramatically increase inflammation on the endothelium and T cell infiltration of cardiac muscle and may account for the observations of increased thrombosis, cardiomyopathy, and other vascular events following vaccination.

    See the comment below.  I am not surprised that attempts were made to immediately kill this little abstract, because it fills in one of the missing pieces about what happens after vaccination, and especially because it provides evidence that what happens does not go away in a few hours or days.  These biomarkers can be followed and the risk the vaccines pose can be better quantified with this type of information.

    As I told a reader, the authors are perfectly clear that these data are from tests normally performed on patients in this clinic.  All the authors did was to collect the results and note that vaccination apparently caused significant elevations in these inflammatory markers, designating increased cardiac risk, and almost certainly causing other adverse conditions to increase... for an extended period.  This is not a clinical trial.  There are no controls, but in a sense, the patients served as their own controls with pre and post vaccination data.  These are not anecdotal data, as more than 500 people were studied.


    Anonymous said...

    (1) Pierre Kory, MD MPA on Twitter: "Tokyo in particular is kicking COVID's ass with IVM - fewest hospitalized since before pandemic. Come on world, wake up wake up wake up https://t.co/nelPEDy9AG" / Twitter

    A pandemic of the vaccinated or Ivermectin ignored? | Columnists | thedesertreview.com

    Anonymous said...

    Next generation Covid vaccines in development might stop Covid? Admitting failure with current Covid vaccines developing many new ones?

    Recurrence of Thrombotic Thrombocytopenic Purpura after mRNA-1273 COVID-19 Vaccine Administered Shortly after COVID-19

    First report of a de novo iTTP episode associated with an mRNA-based anti-COVID-19 vaccination - PubMed

    Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study - PubMed

    China’s COVID vaccines have been crucial — now immunity is waning

    A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants | PNAS

    Next-Generation Bioinformatics Approaches and Resources for Coronavirus Vaccine Discovery and Development-A Perspective Review - PubMed

    Anonymous said...

    Something Really Strange Is Happening At Hospitals All Over America | ZeroHedge

    Lethal Injection; Frontline E.R. Doctor Gives Chilling Account of Unusual Vaccine-Induced Illness « Aletho News

    Anonymous said...

    Minnesota COVID surge creates dangerous ER bottlenecks | MPR News

    Anonymous said...

    'Germany | Dr Thomas Jendges Head of Clinic, Commits Suicide' “COVID-19 Vaccine Is a Genocide”

    In Germany, the Head of the Chemnitz Clinic, Dr Thomas Jendges, committed suicide saying he no longer wants to be part of the Genocide happening via the COVID-19 Vaccine.


    Anonymous said...

    The guy I know who had heart pains after the vaccine is always physically exhausted. He's had a hard life, does a blue-collar crap job, but always did whatever it takes. Now he doesn't give an F, and it got worse after a doctor in his family secretly told him that natural immunity is better than the vaccine.

    John said...


    (1) Pierre Kory, MD MPA (@PierreKory) / Wisconsin lung physician for ivermectin

    (1) Pierre Kory, MD MPA on Twitter: "The fight for the return of physician autonomy in clinical decision making led by Professor Paul Marik is starting to pick up broader international support. Thank you Africa! #westandwithmarik #letdoctorsbedoctors https://t.co/ce6cCkTjNK" / Twitter

    KRolson said...

    Unfortunately those who have had covid and recovered are at a higher risk of damage from the mRNA vaccines. When you consider that the approval studies remove persons who have natural immunity from participating in the studies. Given a very large portion of our population have actually had covid and now have natural immunity.

    The approval testing for the differing age groups doesn't not show anywhere near how many will be injured by being vaccinated.

    Anonymous said...

    The abstract is now linked to the following (unattributed) expression of concern:

    "This article expresses concern regarding abstract “Abstract 10712: Mrna COVID Vaccines Dramatically Increase Endothelial Inflammatory Markers and ACS Risk as Measured by the PULS Cardiac Test: a Warning” which originally
    published November 8, 2021; https://www.ahajournals.org/doi/10.1161/circ.144.suppl_1.10712.

    "Soon after publication of the above abstract in Circulation, it was brought to the American Heart Association Committee on Scientific Sessions Program’s attention that there are potential errors in the abstract. Specifically, there are several typographical errors, there is no data in the abstract regarding myocardial T-cell infiltration, there are no statistical analyses for significance provided, and the author is not clear that only anecdotal data was used.

    "We are publishing this Expression of Concern until a suitable correction is published to indicate that the abstract in its current version may not be reliable."

    This is, to use the proper term, nit-picking. An abstract for a conference proceedings (in this case, the American Heart Association Scientific Session 2021) is necessarily limited in length, and often in word or character count (including punctuation marks and spaces). There is only so much data and detail one can provide in an abstract.

    From what I can gather, this abstract is from a Poster session. The poster itself doesn't appear to be available via the AHA's website, and I couldn't find it anywhere else online. Perhaps the author (Dr Steven Gundry) will make it available at some point and we can all judge for ourselves if these concerns are valid. (Somehow, I doubt it.)