Tuesday, December 15, 2020

Drs. Tyson and Fareed's protocol for treatment and prevention of Covid-19, as discussed during Nov 19 Senate hearing

Dr. George Fareed and his partner Dr. Brian Tyson have together successfully treated over 1,000 Covid patients.  They have been adjusting their protocol over time, and now use both HCQ and ivermectin.  Why not, for a potentially fatal disease?  Why not maximize the potential benefit?  How many drugs was Trump given when he had Covid?

Here is the protocol provided to the Senate Homeland Security and Government Affairs Committee after Dr. Fareed's Nov 19 testimony.

https://www.thedesertreview.com/news/dr-george-fareed-and-dr-brian-tyson-share-hcq-protocol/article_7728815e-3ca2-11eb-8a08-7b4b0156c181.html 

Senator Josh Hawley submitted questions to Dr. Fareed to clarify his testimony for the record. Here is the correspondence between the Senator and Fareed on December 10:

Sen. Hawley: In your testimony, you say that timing is everything when it comes to treatment and that the best time for outpatient treatment to prevent hospitalization comes when “the virus is in a period of maximum replication in the upper respiratory tract.” Can you explain what this would mean for a patient? Would this be five days after exposure, or ten days? Or is it based on symptoms?  

Dr. Fareed: The earlier the treatment can be started after the start of the infection, the better and more rapid the recovery (as well as the reduction in the risk of spread/contagious period). This would mean that the patient should optimally start the treatment in the first 4 days of the infection and within five days of exposure. It usually is based on symptoms which start within 1-4 days of viral entry into the upper respiratory system. Even starting the multi-faceted treatment later (7-10 days after infection) is also very worthwhile if severe pneumonia necessitating hospitalization has not yet set in.

Sen. Hawley: In your experience, are patients typically coming in to get treated at this point in their illness? And if not, what do you think we need to do to encourage high-risk individuals to seek outpatient treatment and care? 

Dr. Fareed: More patients are coming in to get treated or contacting me from afar for treatment when they can’t receive the treatment in their local communities. Sadly, many infected people and primary care doctors and doctors in ERs follow the NIH and Dr. Fauci stipulations with no effective treatments offered. We need to have the NIH/FDA/CDC formally acknowledge the importance of early treatment with moderately acting, safe anti-virals so readily available. When (if ever) that happens, everything would improve dramatically. Thank you, Senator Hawley,  for all your efforts and for allowing me to respond to these excellent questions.

The following is the protocol Drs. Fareed and Tyson have jointly developed as most effective for their COVID-19 patients:

Fareed/Tyson COVID-19 Treatment Protocol

HCQ 200 mg tabs #16 (HCQ = hydroxychloroquine)

Zinc sulfate 22O mg (or elemental Zinc 50 mg) # 15

Azithromycin 500 mg # 5 (or Z pack) or

Doxycycline 100 mg # 10)

Ivermectin 3 mg tabs #8

Aspirin 325 mg tabs #30 

Day 1 - HCQ 2 tabs twice a day 

Zinc sulfate tab twice a day

(Azithromycin tab one per day or doxycycline cap twice a day)

Ivermectin 12 mg on day 1 only

Aspirin 325 mg 

Days 2-5 

HCQ tab 3 times a day

Zinc sulfate 3 times a day

(Azithromycin tab daily or doxycycline cap twice a day)

Aspirin 325 mg daily

Ivermectin 12 mg on day 3 if symptoms warrant 

Prednisone 60 mg daily x 5-7 days or

Dexamethasone 4 mg bid if wheezing /SOB

Budesonide 0.5-1mg/2ml vía nebulizer bid 

Vitamin D3 5000 iu daily

Pepcid 20 mg daily

Continue daily Aspirin 325 mg

Over the counter prevention:

Elemental Zinc 25 mg once a day

Vitamin D 4000 iu once a day

Vitamin C 1000 mg once a day 

Quercetin 500 mg once a day 

If Quercetin is unavailable, then use Epigallocatechin-gallate (EGCG) 400mg once a day

Dr. Fareed also included Dr. Zelenko’s (Twitter: @zev_dr) COVID-19 Prophylaxis Protocol: 

Prophylaxis is an action taken to prevent or protect against a specified disease. Greek in origin, from the word "phylax", meaning "to guard" and "watching." 

Low Risk Patients

Young healthy people do not need prophylaxis against COVID-19. In young and healthy people, this infection causes mild cold-like symptoms. It is advantageous for these patients to be exposed to COVID-19, build up their antibodies and have their immune system clear the virus. This will facilitate the development of herd immunity and help prevent future COVID-19 pandemics. However, if these patients desire prophylaxis against COVID-19, then they should take the protocol noted below. 

Moderate-Risk Patients

Patients from this category are healthy but have high potential viral-load exposure. This group includes medical personnel, caregivers of high-risk patients, people who use public transportation, first responders and other essential personnel who are crucial to the continued functioning of society. These patients should be encouraged to take prophylaxis against COVID-19 in accordance with the protocol noted below.

High-Risk Patients

Patients are considered high risk if they are over the age of 60, or if they are younger than 60 but they have comorbidities, that is, they have other health conditions that put them at risk. These patients have between a 5 to 10 percent mortality rate if they are infected with COVID-19. These patients should be strongly encouraged to take prophylaxis against COVID-19 in accordance with the protocol noted below. 

Protocol for Low and Moderate Risk Patients:

Elemental Zinc 25 mg once a day[1]

Vitamin C 1000 mg once a day[2]

Quercetin 500 mg once a day 

If Quercetin is unavailable, then use Epigallocatechin-gallate (EGCG) 400 mg once a day[3]

Protocol for High-Risk Patients:

Elemental Zinc 25 mg once a day 

Hydroxychloroquine (HCQ[4]) 200 mg once a day for five days, then once a week

If HCQ is unavailable, then use the Protocol for Low and Moderate Risk Patients.

[1]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365891/

[2]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318306/

[3]https://pubs.acs.org/doi/10.1021/jf5014633

[4]https://www.preprints.org/manuscript/202007.0025/v1

2 comments:

Rob Bots said...

Dear Dr. Nass,
Can you please comment also on Ivermectine.
link: https://covid19criticalcare.com/i-mask-prophylaxis-treatment-protocol/i-mask-protocol-translations/
Dr. Robert Bots
Gynaecologist
retired

Meryl Nass, M.D. said...

IMHO, both the iMASK and MATH and Fareed protocols are effective. They differ slightly. Fareed treats outpatients while the iMASK/MATH group are mostly ICU physicians. By the time a patient gets to the ICU, HCQ no longer works.

But HCQ works very well early in the illness, especially when coupled with zinc and either doxycycline or azithromycin.