Theoretically better. Based on antigens and titers. Not on cases and cases prevented:
The FDA approved the first three-antigen hepatitis B vaccine (PreHevbrio) to prevent infection from all known subtypes in adults, VBI Vaccines announced on Wednesday.
Approval for the recombinant vaccine -- which contains the S, pre-S1, and pre-S2 hepatitis B virus (HBV) surface antigens -- was based on data from two phase III trials that compared the safety and immunogenicity against the single-antigen Engerix-B vaccine.
In PROTECT, the three-antigen vaccine demonstrated higher seroprotection rates versus Engerix-B among all adults (91% vs 77%, respectively) and among those 45 and older (89% vs 73%). In CONSTANT, a pooled analysis of adults who received PreHevbrio had numerically higher seroprotection rates compared to the Engerix-B group (99% vs 95%).
https://www.medpagetoday.com/gastroenterology/hepatitis/95983
As I showed recently , there is no demonstrated increase of Hepatitis B in the US, according to CDC, only estimates of a potential problem.
Given the massive increase in iv drug abuse since 2009, I would have expected an increase in new Hepatitis B infecctions, but CDC did not produce any evidence that there is one. But if you are monogamous or not sexually active, and don't use dirty needles, the chance of getting Hepatitis B is close to zero.
Will these be the next mandated vaccines?
1 comment:
More then 8% of Haitians have chronic HBV infection.
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https://www.cdc.gov/hepatitis/hbv/pdfs/hbv_figure3map_08-27-08.pdf
Estimated 15,599 + Haitians have entered US since January. 8% of 15,599 is 1,248 with chronic HBV infection.
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https://www.theepochtimes.com/644-percent-increase-in-haitians-illegally-crossing-us-border_3929289.html
300 + Haitians have been flown dead of night into Portland, Maine. At 8% that’s 24 new cases of chronic HBV in Portland, Maine.
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https://apnews.com/article/immigration-haiti-portland-africa-angola-8077f0f644c6878f73bdc30b76af813a
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